바로가기 메뉴
본문내용 바로가기

학회지

Journal of Neurosonology 2012; 4 ( 1) : 1-7

전문보기
초음파혈전용해술의 현재와 미래
  • 김영대
  • 세브란스병원 뇌졸중센터, 연세대학교 의과대학 신경과학교실

Current Status of Sonothrombolysis and its Future
  • Young Dae Kim
  • Department of Neurology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
Thrombolytic treatment with intravenous (IV) tissue plasminogen activator (t-PA) is a proven therapy in acute ischemic stroke patients. Successful recanalization is a strong determinant for favorable outcome in patients who received thrombolytic treatments. In the last few decades, thrombolysis with ultrasound has been tested whether this modality can improve the successful recanalization rate or clinical outcomes. Three different ultrasound technologies including transcranial Doppler, transcranial color-coded sonography, and low-frequency ultrasound were used to increase the thrombolytic efficacy of IV t-PA. Because microbubbles can lower the amount of ultrasound energy needed for acoustic cavitation, concomitant use of microbubbles with ultrasound has been also tested for the presence of additional benefits in sonothrombolysis. This article reviews the present status of sonothromboolysis in acute ischemic stroke and discusses its future.

Journal of Neurosonology 4(1):1-7, 2012
Key Words: Stroke, Sonothrombolysis